After solving a mystery that involves a mummy, Scooby-Doo, Shaggy, Fred, Daphne, and Velma go to Blowout Beach where they find that there are ghost pirates haunting the location.
- Frank Welker as Scooby-Doo and Fred Jones
- Matthew Lillard as Shaggy Rogers
- Grey Griffin as Daphne Blake and Ghost of Bingo Bell
- Kate Micucci as Velma Dinkley
- Jeff Bennett as Deputy and Museum Tour Guide
- Kate Higgins as Brenda
- Josh Keaton as Chad Holdout and Tommy
- Tom Kenny as Rob Holdout
- Natalie Lander as Krissy Holdout
- Jack McBrayer as Police Officer
- Kevin Michael Richardson as Ghost of Captain Bash and Sheriff
- Fred Tatasciore as Dwight Monkfish
- Iqbal Theba as Dr. Najib
- Hynden Walch as Mitzi Capaletto
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