When Mike's best friend, Will Byers, mysteriously went missing, he and his other friends, Lucas and Dustin, made it their mission to find him. However, while searching for Will, they stumbled upon an escaped girl named Eleven instead. Mike soon discovered that she knew something about Will's disappearance and enlisted her help in finding him. During their time together, Mike and Eleven formed a strong bond and quickly grew to like each other. Once Will was found, Mike was happy that he had returned home safely; however, he was greatly devastated by Eleven's sacrifice to defeat the Demogorgon.
Still devastated by Eleven's disappearance one year later, Mike called for her every night while also assisting Will with a new supernatural issue. Eventually, he reunited with Eleven. He, along with his friends and Steve, then worked on burning the sprawling network of another inter-dimensional threat, using it as a distraction for Eleven to close the Gate for good. Mike later attended the Snow Ball dance with Eleven, which he had promised her the previous year.
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|Sets||75810 The Upside Down \ ST-1 Castle Byers \ Comic-Con Exclusive Barb Giveaway|
|Minifigures||Demogorgon \ Dustin Henderson \ Eleven \ Jim Hopper \ Joyce Byers \ Lucas Sinclair \ Michael (Mike) Wheeler \ Will Byers \ Barbara (Barb) Holland|