- "Raaargh! Now it's personal! Get ready for some hand to hand to hand to hand fighting!"
- ―Spyclops, after the destruction of his Spider Mech
Spyclops has a yellow head with printing that depicts spiderlike cybernetic parts, which are silver. His face features an angry expression showing teeth. He has some stubble and green eyes. On his forehead is a purple lens. He wears a dark red cap and mechanical spider legs on his back. He wears a flame yellowish orange jumpsuit depicting the uniform of an exterminator. Over his suit, he has several cybernetic parts on his body. His torso printing has a silver spider in the middle, suspenders at the sides of this and green bottles on the straps. His left leg is the same color of his suit while the right one is grey, both of these have belts on the knees and pouches on the upper legs. His accessory is a spray bottle with transparent yellow-green liquid in it.
Spyclops was once a former exterminator that got corrupted by AntiMatter, after being sucked in one of his portals. He was first seen at Ultra Agents: The Antimatter Missions, when he was ordered by AntiMatter to attack the newest Ultra Agents' HQ, using his army of Spyders, an army of mechanical spiders. He fought riding his mech against the agents, but he lost the battle and was captured in a forcefield cell.
Later, during the attack at Professor Brainstein's lab, he was found talking to Invizable, just before he freed all of the captured super villains. Spyclops rode the Infearno's hoverboard to escape to the sky, which he returned to his owner after they managed to reach the city. He was seen capturing the civilians for AntiMatter's arrival, after this, he fought against Caila Phoenix and the UltraCopter, who managed to defeat Spyclops, along with all of the super villains. Later, after the battle, he was seen alongside his fellow villains, all captured in blue containers.
- Ultra Agents: The Antimatter Missions
- Mission 1: New Base, New Gear & New Enemies
- Mission 2: Security Breach
- Mission 4: The Trap is Sprung
- Mission 5: Antimatter Strikes
- The preliminary Spyclops had a yellow cap and OverBorg's head.
- His name is a pun of "spider" and "cyclops."
- His LEGO.com description reveals that he was once an exterminator, but was corrupted by AntiMatter's portals, causing him to become a Super Villain, he intends to turn Astor City into an electronic bug hive.
- His voice is slightly high pitched and has a synthesized tone to it. He also speaks with a hint of a Brooklyn accent.
- His voice actor was not credited in Ultra Agents: The Antimatter Missions.